Research Associate I/II

Location: Avidity Biosciences LLC, 10975 N. Torrey Pines Road, La Jolla, CA  92037
Position type: Full time, Research Associate I/II
Required education: Biology, Biochemistry, Bioengineering

Company Description:
Avidity Biosciences is a privately held biotech company pioneering Antibody Oligonucleotide Conjugates (AOC™). AOCs combine the tissue selectivity of monoclonal antibodies and the precision of oligonucleotide-based therapeutics to overcome barriers to the delivery of oligonucleotides and target genetic drivers of disease. We are advancing a pipeline of therapeutic programs focused on rare muscle disorders and other serious diseases. Our lead programs are directed to the development of therapeutics to treat patients with Duchenne muscular dystrophy and myotonic dystrophy.  More information about Avidity Biosciences can be found on our website  Please submit your resume to to apply.

Job Description:
We are seeking a Research Associate I/II to join our Duchenne Muscular Dystrophy research team. The ideal candidate would have familiarity with:

  • Culturing immortalized and primary cells
  • Isolating RNA and proteins from tissue samples
  • Quantifying RNA levels using RT-qPCR
  • Monitoring RNA processing using qPCR, gel electrophoresis, or digital PCR
  • Quantitative Western blot analysis
  • ELISA-based functional assays
  • Immunohistochemistry
  • FACS

Required Experience and Skills:

  • General understanding of RNA processing
  • Hands-on experience with cell culture, isolating RNA and proteins from tissue samples, qPCR, ELISA, Western blot analysis
  • Ability to develop/execute quantitative assays
  • Familiarity with muscle cultures or muscle related diseases is a plus
  • Reliable, organized, excellent record keeping
  • Demonstrated ability to multitask within a matrix and team environment