Program/IndicationTargetDiscovery/Lead OptimizationIND EnablingPhase 1/2
AOC 1001
Myotonic Dystrophy Type 1 (DM1)
DMPK

AOC FSHD
Facioscapulohumeral Muscular Dystrophy (FSHD)
DUX4

Clinical trial initiations planned for 2022

AOC 1044
Duchenne Muscular Dystrophy (DMD)
Exon 44 Dystrophin

Clinical trial initiations planned for 2022

Next AOC DMD Programs
 
Exon 51 Dystrophin

 
Exon 45 Dystrophin

AOC Muscle Atrophy
Muscle Atrophy*
MuRF1

AOC Pompe Disease
Pompe Disease
GYS1

Program/IndicationTargetStage
AOC 1001
Myotonic Dystrophy Type 1 (DM1)
DMPK Phase 1/2
AOC FSHD
Facioscapulohumeral Muscular Dystrophy (FSHD)
DUX4 Discovery/Lead Optimization
AOC 1044
Duchenne Muscular Dystrophy (DMD)
Exon 44 Dystrophin IND Enabling
Next AOC DMD Programs
 
Exon 51 Dystrophin Discovery/Lead Optimization
 
Exon 45 Dystrophin Discovery/Lead Optimization
AOC Muscle Atrophy
Muscle Atrophy*
MuRF1 Discovery/Lead Optimization
AOC Pompe Disease
Pompe Disease
GYS1 Discovery/Lead Optimization

* Opportunity for a rare disease indication